If there is one place that you need to make reservation to drink beer is BBC (Bosphorus Brewing Company)
This is place is so popular amongst both locals, expats and business travellers. Locals are happy to find different tastes of beer and pork dishes, and the foreigners are happy because they can find what they are missing in Istanbul.
The interior, beer and food menu just resemble classic British Pubs. The beer is brewed in their own “micro” brewery. Istanbul Pale Ale is a traditional English cask Ale, Haliç Gold is a spicy and strong ale, B4 is a more bitter beer. They are all served in their special glasses.
Food is good, a bit expensive though. They serve both a bar menu (includes sousages, cheese plates, chicken wings) and a rich lunch / dinner menu. You can choose fish & chips, lasagne, duck and burgers. All of which are good and go well with the beer.
BBC also suggests which beer goes best with which choice of food.
If you are for a business trip to Istanbul and have a meeting around Mecidiyeköy area, this is a good place to have a beer after the meeting.