Probably the best nightclub in town is called Epicentar. It has two venues, one closed winter space and one open-air, used during the summer period. The winter club is located in the downtown, very close to the St. Clement of Ohrid church.
You’ll find the place to be the most laid back and lively dance floor in town. It does require you to be decently dressed, but it’s not a suit and tie club. It’s electronic music venue, opened on Thursday, Friday and Saturday. The program is updated regularly on their Facebook page, with the bigger “names” announced couple of weeks earlier.
Most likely you’ll come across some popular figures from Macedonia, so you can easily take pictures with them and talk a little. Everything is, as I said, very-very chilled and casual. It tends to be very crowded, so make a reservation or get there early and be ready to wait a little bit. Once you’re in, get your drinks from the bars, put your groove to use, and be ready to dance until dawn. If you want a party, this is the place to be.